Figure 6

Change in mucosal bacterial compositions by antibiotic cocktail (AB) and fluconazole (AF) treatment.
(A) The 16s rDNA levels in the colonic mucosa of AB mice were significantly decreased relative to normal and AF mice. (B) The bacterial Shannon index was significantly increased in the mucosa of AF mice relative to normal and AB mice. (C) Partial least-squares discriminant analysis (PLS-DA) scores plot based on the relative abundance of bacterial OTUs (97% similarity level) in the colonic mucosa of normal, AB and AF mice. *P < 0.05, **P < 0.01, ***P < 0.001.