Table 1 Clinicopathological characteristics of colorectal cancer patients according to age groups.
From: The prognostic factors and multiple biomarkers in young patients with colorectal cancer
Characteristic | WC | P | SEER | P | LC | P | |||
|---|---|---|---|---|---|---|---|---|---|
≤50 years n = 530 (%) | >50 years n = 5388 (%) | ≤50 years n = 43,236 (%) | >50 years n = 459,766 (%) | ≤50 years n = 55 (%) | >50 years n = 959 (%) | ||||
Gender | |||||||||
Male | 232 (43.8) | 3,333 (61.9) | <0.001 | 22,803 (52.7) | 231,126 (50.3) | <0.001 | 24 (43.6) | 525 (54.7) | 0.108 |
Female | 298 (56.2) | 2,055 (38.1) | 20,433 (47.3) | 228,640 (49.7) | 31 (56.4) | 434 (45.3) | |||
Locationa | |||||||||
Right Colon | 65 (12.3) | 1221 (22.7) | <0.001 | 16,021 (38.5) | 171,793 (38.8) | <0.001 | 8 (14.5) | 292 (30.4) | 0.007 |
Left Colon | 86 (16.2) | 780 (14.5) | 13,074 (31.5) | 139,756 (31.6) | 16 (29.1) | 154 (16.1) | |||
Rectum | 379 (71.5) | 3387 (62.8) | 12,476 (30.0) | 130,975 (29.6) | 31 (56.4) | 513 (53.5) | |||
Missing | 0 | 0 | 1,665 | 17,242 | 0 | 0 | |||
Tumour numbers | |||||||||
Single | 185 (96.9) | 995 (90.5) | 0.006 | 35,423 (81.9) | 313,627 (68.2) | <0.001 | 41 (95.3) | 747 (94.3) | 1.000 |
Multiple | 6 (3.1) | 104 (9.5) | 7,810 (18.1) | 146,091 (31.8) | 2 (4.7) | 45 (5.7) | |||
Missing | 339 | 4,289 | 3 | 48 | 12 | 167 | |||
TNM stageb | |||||||||
I | 72 (14.1) | 1262 (23.6) | <0.001 | 6,495 (24.0) | 70,291 (27.5) | <0.001 | 7 (13.0) | 157 (16.8) | 0.455 |
II | 115 (22.6) | 1741 (32.5) | 6,165 (22.8) | 75,163 (29.4) | 21 (38.9) | 345 (37.0) | |||
III | 144 (28.3) | 1500 (28.0) | 8,058 (29.7) | 62,180 (24.3) | 14 (25.9) | 290 (31.1) | |||
IV | 178 (35.0) | 853 (15.9) | 6,373 (23.5) | 47,931 (18.8) | 12 (22.2) | 141 (15.1) | |||
Othersc | 21 | 32 | 16,145 | 204,201 | 1 | 26 | |||
Tumour growth pattern | |||||||||
Expansive | 122 (40.8) | 599 (28.5) | <0.001 | / | / | 15 (40.5) | 356 (49.9) | 0.269 | |
Infiltrative | 177 (59.1) | 1,503 (71.5) | / | / | 22 (59.5) | 358 (50.1) | |||
Missing | 231 | 3,286 | / | / | 18 | 245 | |||
Histological type | |||||||||
Non-mucinous | 379 (71.5) | 4173 (77.4) | 0.002 | 36,931 (88.7) | 391,999 (90.5) | <0.001 | 49 (90.7) | 854 (90.2) | 0.893 |
Mucinousd | 151 (28.5) | 1215 (23.6) | 4,694 (11.3) | 41,114 (9.5) | 5 (9.3) | 93 (9.8) | |||
Others | 0 | 0 | 1,611 | 26,653 | 1 | 12 | |||
Differentiatione | |||||||||
Well | 25 (5.7) | 130 (2.7) | <0.001 | 4,112 (13.3) | 49,038 (14.8) | <0.001 | 2 (3.7) | 60 (6.3) | 0.754 |
Moderately | 284 (64.5) | 3502 (72.1) | 20,013 (64.7) | 217,711 (65.8) | 36 (66.7) | 626 (66.1) | |||
Poorly+undifferentiated | 131 (29.8) | 1226 (25.2) | 6,811 (22) | 64,133 (19.4) | 16 (29.6) | 261 (27.6) | |||
Missing | 90 | 530 | 12,300 | 128,884 | 11 | 2 | |||
Surgical type | |||||||||
Radical | 518 (97.7) | 5130 (95.2) | 0.008 | / | / | 44 (80.0) | 790 (84.8) | 0.593 | |
Palliative+unresectable | 12 (2.3) | 258 (4.8) | / | / | 11 (20.0) | 164 (17.2) | |||
Missing | 0 | 0 | / | / | 0 | 5 | |||
Radiotherapy | |||||||||
No | / | / | 35,153 (82.2) | 412,124 (91.0) | <0.001 | 30 (69.8) | 617 (79.1) | 0.146 | |
Yes | / | / | 7,622 (17.8) | 40,814 (9.0) | 13 (30.2) | 163 (20.9) | |||
Missing | / | / | 461 | 6,828 | 12 | 179 | |||
Chemotherapy | |||||||||
No | / | / | / | / | 42 (95.5) | 694 (89.8) | 0.221 | ||
Yes | / | / | / | / | 2 (4.5) | 79 (10.2) | |||
Missing | / | / | / | / | 11 | 186 | |||
