Table 1 Differentially expressed DC signature genes in E2-2 knockdown GEN2.2 cells.
From: Characterization of species-specific genes regulated by E2-2 in human plasmacytoid dendritic cells
Gene symbol | Gene title | Ratio |
|---|---|---|
cDC signature genes | ||
LY86 | lymphocyte antigen 86 | 7.6826 |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 4.7388 |
EMP1 | epithelial membrane protein 1 | 3.6011 |
HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | 2.6273 |
PSEN2 | presenilin 2 (Alzheimer disease 4) | 2.533 |
HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 | 2.4325 |
DISC1 | disrupted in schizophrenia 1 | 2.4288 |
CIITA | class II, major histocompatibility complex, transactivator | 2.4064 |
CSRP1 | cysteine and glycine-rich protein 1 | 2.2192 |
PPM1H | protein phosphatase 1H (PP2C domain containing) | 2.2087 |
KCNMB1 | potassium large conductance calcium-activated channel, subfamily M, beta member 1 | 2.2002 |
ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 2.1907 |
CENTA2 | ArfGAP with dual PH domains 2 | 2.1818 |
IER5 | immediate early response 5 | 2.1753 |
NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) | 2.1598 |
SPRY2 | sprouty homolog 2 (Drosophila) | 2.0886 |
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 2.0514 |
pDC signature genes | ||
GZMB | granzyme B | 0.1093 |
RGS7 | regulator of G-protein signaling 7 | 0.2939 |
COBLL1 | COBL-like 1 | 0.3393 |
SRPX | sushi-repeat-containing protein, X-linked | 0.3716 |
TCL1B | T-cell leukemia/lymphoma 6 | 0.3829 |
LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 | 0.417 |
MAP1A | microtubule-associated protein 1A | 0.4371 |
DUSP5 | dual specificity phosphatase 5 | 0.4389 |
MYB | v-myb myeloblastosis viral oncogene homolog (avian) | 0.4568 |
CLEC4C | C-type lectin domain family 4, member C | 0.4609 |
MLF1IP | MLF1 interacting protein | 0.461 |
SLC12A3 | solute carrier family 12, member 3 | 0.4707 |
RRBP1 | transforming growth factor, beta-induced, 68kDa | 0.4711 |
TGFBI | ribosome binding protein 1 homolog 180kDa (dog) | 0.4711 |
KCNK1 | potassium channel, subfamily K, member 1 | 0.4809 |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 2.0998 |
RASGEF1B | RasGEF domain family, member 1B | 2.4254 |
DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 3.4648 |