Table 1 Differentially expressed DC signature genes in E2-2 knockdown GEN2.2 cells.

From: Characterization of species-specific genes regulated by E2-2 in human plasmacytoid dendritic cells

Gene symbol

Gene title

Ratio

cDC signature genes

LY86

lymphocyte antigen 86

7.6826

HLA-DQA1

major histocompatibility complex, class II, DQ alpha 1

4.7388

EMP1

epithelial membrane protein 1

3.6011

HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

2.6273

PSEN2

presenilin 2 (Alzheimer disease 4)

2.533

HLA-DPB1

major histocompatibility complex, class II, DP beta 1

2.4325

DISC1

disrupted in schizophrenia 1

2.4288

CIITA

class II, major histocompatibility complex, transactivator

2.4064

CSRP1

cysteine and glycine-rich protein 1

2.2192

PPM1H

protein phosphatase 1H (PP2C domain containing)

2.2087

KCNMB1

potassium large conductance calcium-activated channel, subfamily M, beta member 1

2.2002

ENTPD1

ectonucleoside triphosphate diphosphohydrolase 1

2.1907

CENTA2

ArfGAP with dual PH domains 2

2.1818

IER5

immediate early response 5

2.1753

NAB2

NGFI-A binding protein 2 (EGR1 binding protein 2)

2.1598

SPRY2

sprouty homolog 2 (Drosophila)

2.0886

ATP1B1

ATPase, Na+/K+ transporting, beta 1 polypeptide

2.0514

pDC signature genes

GZMB

granzyme B

0.1093

RGS7

regulator of G-protein signaling 7

0.2939

COBLL1

COBL-like 1

0.3393

SRPX

sushi-repeat-containing protein, X-linked

0.3716

TCL1B

T-cell leukemia/lymphoma 6

0.3829

LILRA4

leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4

0.417

MAP1A

microtubule-associated protein 1A

0.4371

DUSP5

dual specificity phosphatase 5

0.4389

MYB

v-myb myeloblastosis viral oncogene homolog (avian)

0.4568

CLEC4C

C-type lectin domain family 4, member C

0.4609

MLF1IP

MLF1 interacting protein

0.461

SLC12A3

solute carrier family 12, member 3

0.4707

RRBP1

transforming growth factor, beta-induced, 68kDa

0.4711

TGFBI

ribosome binding protein 1 homolog 180kDa (dog)

0.4711

KCNK1

potassium channel, subfamily K, member 1

0.4809

ENPP2

ectonucleotide pyrophosphatase/phosphodiesterase 2

2.0998

RASGEF1B

RasGEF domain family, member 1B

2.4254

DAB2

disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

3.4648