Figure 1 | Scientific Reports

Figure 1

From: Spinal mechanisms underlying potentiation of hindpaw responses observed after transient hindpaw ischemia in mice

Figure 1

Reduced mechanical thresholds for hindpaw-withdrawal reflex.

(a) Application of high pressure (250 mm Hg) to the left thigh. (b) Mechanical thresholds for left hindpaw-withdrawal reflex before and after ischemic or sham treatment applied to the left thigh. Mean ± SEM are shown. (c) Mechanical thresholds for hindpaw-withdrawal reflex after hindpaw ischemia in mice with spinal application of LY354740 (10 nM, 5 μl) or saline alone. (d) Comparison of the thresholds for the left hindpaw-withdrawal reflex at 2 h after ischemic or sham treatment, with or without spinal application of LY354740. In the ischemia group, data were mixed in mice with or without spinal application of saline. In the sham-treated group, data were mixed in mice with sham treatment to the left thigh or to the right thigh.

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