Table 2 Top 13 secreted factors over-represented in BM-MSCs.
Secreted factors | mRNA Refseq | P-value | Mean ratio (BM-MSCs/iPSC-MSCs) | Involved biological process |
|---|---|---|---|---|
MMP-15 | NM_002428 | 0.024 | 42.55319 | Phosphoprotein, transmembrane, glycoprotein, calcium ion binding, polymorphism, disulfide bond |
Activin RII A/B | NM_001106 | 0.002 | 5.885815 | Cell differentiation |
EGF R (ErbB1) | NM_005228 | 0.0603 | 5.630631 | Cell migration, cell proliferation, cell cycle, apoptosis |
Activin A | NM_002192 | 0.0403 | 5.51572 | mesoderm induction, cellular proliferation and differentiation, cell survival |
AR (Amphiregulin) | NM_001657 | 0.03 | 4.512635 | Cell proliferation, mitogen |
CD30 Ligand | NM_001244 | 0.0328 | 3.318951 | Cell proliferation, apoptosis |
S100 A8/A9 | NM_002965 | 0.0844 | 3.063725 | Inflammatory response, cell migration |
CCR7 | NM_001838 | 0.0167 | 2.783964 | Inflammatory response, cell migration of memory T cells |
Glypican 3 | NM_001164617 | 0.0585 | 2.45821 | Cell division, cell differentiation |
PDGF R alpha | NM_006206 | 0.0827 | 2.278943 | Cell migration, cell proliferation |
VEGF R2 (KDR) | NM_002253 | 0.069 | 2.198769 | Cell migration, cell proliferation |
SIGIRR | NM_021805 | 0.0641 | 2.042901 | Inflammatory response |
Chem R23 | NM_001142345 | 0.0029 | 2.024701 | Cell migration |
