Table 4 Number and percentage of cases with and without a concordant cancer in the family among individuals at age ≥ 60 years.
Cancer site | Number of cases (%) with a negative family history | Number of cases (%) with concordant cancers among first-degree relatives | |
|---|---|---|---|
2 affected FDR1 | 3 or more affected FDRs | ||
Upper aerodigestive tract | 2733 (97.1) | 81 (2.9) | 2 (0.1) |
Esophagus | 1251 (98.2) | 23 (1.8) | 0 (0) |
Stomach | 1958 (93.3) | 133 (6.3) | 7 (0.3) |
Small intestine | 611 (97.6) | 14 (2.2) | 1 (0.2) |
Colorectum | 12934 (86.2) | 1940 (12.9) | 126 (0.8) |
Liver | 2280 (96.3) | 87 (3.7) | 1 (0.0) |
Pancreas | 2823 (95.9) | 116(3.9) | 4 (0.1) |
Lung | 10215 (89.8) | 1124 (9.9) | 42 (0.4) |
Breast | 16469 (85.6) | 2573 (13.4) | 204 (1.1) |
Cervix | 623 (98.9) | 7 (1.1) | 0 (0) |
Endometrium | 4458 (96.1) | 179 (3.9) | 4 (0.1) |
Ovary | 2336 (96.6) | 80 (3.3) | 2 (0.1) |
Prostate | 29273 (78.1) | 7148 (19.1) | 1071 (2.9) |
Testis | 108 (99.1) | 1 (0.9) | 0 (0) |
Kidney | 3099 (96.6) | 108 (3.4) | 2 (0.1) |
Urinary bladder | 5711 (93.7) | 378 (6.2) | 9 (0.2) |
Melanoma | 5251 (94.5) | 288 (5.2) | 15 (0.3) |
Skin, squamous cell | 4564 (93.5) | 307 (6.3) | 12 (0.3) |
Nervous system | 3364 (96.6) | 117 (3.4) | 3 (0.1) |
Thyroid gland | 504 (97.9) | 11 (2.1) | 0 (0) |
Endocrine glands | 1764 (97.8) | 37 (2.1) | 2 (0.1) |
Non-Hodgkin lymphoma | 4072(96.4) | 148 (3.5) | 3 (0.1) |
Hodgkin lymphoma | 222 (99.1) | 2 (0.9) | 0 (0) |
Myeloma | 1690 (97.2) | 48 (2.8) | 0 (0) |
Leukemia | 3366 (95.3) | 162 (4.6) | 3 (0.1) |
