Figure 6

Changes in growth plate chondrocyte function in Col2-Opg mice.
(A) TUNEL staining was performed using 4-week-old WT and Col2-Opg mice (red arrows: apoptotic chondrocytes). (B) Real-time PCR was performed to determine changes in expression of Col2a1, Col10a1, Mmp13, ostocalcin and Alp in sternal chondrocytes derived from WT and Col2-Opg mice. Data are presented as means ± SD (n = 3 per group).