Figure 3
From: Facile Discovery of a Diverse Panel of Anti-Ebola Virus Antibodies by Immune Repertoire Mining
Functional characterization of IgG antibodies isolated via mining of the PLN CD138+ B cell repertoire.
(a) Binding to EBOV VLPs for antibodies encoded by the seven most frequently observed CDRH3:CDRL3 clonotypes from the sequenced PLN CD138+ B cell repertoires of each mouse. (b) Binding to purified EBOV recombinant GP for select antibodies as determined by ELISA. Binding to BSA as a control is shown in correspondingly colored dashed lines. Error bars represent the standard error of the mean for three technical replicates.
