Figure 5
From: Facile Discovery of a Diverse Panel of Anti-Ebola Virus Antibodies by Immune Repertoire Mining
Binding of cross-reactive antibodies isolated via mining of the PLN CD138+ B cell repertoire to wild type EBOV, BDBV and SUDV viruses.
ELISA assays using antibodies ZM1.7, ZM2.5, ZM2.6 and KZ52 for the detection of (a) wild type Ebola virus; (b) wild type Bundibugyo virus; and (c) wild type Sudan virus. Assays were performed in two technical replicates. Lines represent measurements fitted via 4-parameter logistic nonlinear regression for EC50.
