Figure 4
From: The antiviral drug ganciclovir does not inhibit microglial proliferation and activation
The effects of ganciclovir were investigated on the proliferation and viability of microglia in vitro using primary microglia cultures.
Different doses of ganciclovir (0.05–1 mM) did not change microglial proliferation as shown by analysis of BrdU+ cells (A,B). The percentage of annexin V+ (early apoptotic), annexin V+ PI+ (late apoptotic) and PI+ (necrotic) cells was not changed by ganciclovir indicating that ganciclovir did not influence survival of cells. Each data represents the mean ± SEM, n = 4.
