Table 5 Adjusted mean BMD level by high and low renal function and the use of Chinese herb.

From: Association of Renal Function and Menopausal Status with Bone Mineral Density in Middle-aged Women

Renal function

Overall (n = 1,419)

Not use of Chinese herb (n = 1,296)

Use of Chinese herb (n = 120)

P interaction

n

Adjusted BMDa Mean ± S.E. (g/cm2)

P c

n

Adjusted BMD Mean ± S.E. (g/cm2)

P c

n

Adjusted BMD Mean ± S.E. (g/cm2)

P c

eGFR (mL/min/1.73 m2)

 ≥80b

885

1.18 ± 0.14

0.001

802

1.19 ± 0.13

0.001

81

1.17 ± 0.14

0.51

0.36

 <80b

534

1.21 ± 0.14

494

1.21 ± 0.14

39

1.15 ± 0.16

CCr (mL/min)

 ≥78b

661

1.22 ± 0.13

<0.0001

604

1.22 ± 0.13

<0.0001

55

1.18 ± 0.14

0.28

0.57

 <78b

758

1.17 ± 0.14

692

1.17 ± 0.14

65

1.15 ± 0.16

  1. Abbreviations: S.E., standard error; BMD, bone mineral density; eGFR, estimated glomerular filtrationrate; CCr, creatinine clearance rate. Numbers in bold indicated statistical significant findings.
  2. aAdjusted BMD was obtained from linear regression models adjusting for age, menopausal status (yes/no), body weight (for eGFR model only), hypertension, low-density lipoprotein cholesterol, fasting glucose, serum alkaline phosphatase, serum uric acid, height (for CCr model only) and use of Chinese herb (yes/no).
  3. bThe cutoff values of eGFR (80 mL/min/1.73 m2) and CCr (78 mL/min) were determined by maximizing the Youden’s index.
  4. cP-values were obtained from Mann-Whitney U test.
Back to article page