Figure 1

Changes in cardiovascular and heart rate patterns.
Time sequence of changes in mean arterial blood pressure (MAP, mmHg), fetal heart rate (FHR, bpm), the standard deviation of RR intervals (SDNN) and sample asymmetry from 24 hours before until 96 hours after the start of infusions. Dashed vertical lines show the timing of stepwise low-dose infusions, whereas solid vertical lines show the timing of bolus administration. Data are 1 hour means ± SEM. αp < 0.05, LPS-hypotension vs. saline controls; βp < 0.05, LPS-hypotension vs. LPS-normotension.