Table 1 Fetal pH, blood gases and metabolites.

From: Subclinical decelerations during developing hypotension in preterm fetal sheep after acute on chronic lipopolysaccharide exposure

 

Baseline

Before Bolus 1

Bolus 1 + 2 h

Bolus 1 + 6 h

Bolus 2 + 6 h

pH

 Saline control

7.37 ± 0.01

7.36 ± 0.01

7.36 ± 0.01

7.36 ± 0.01

7.36 ± 0.01

 LPS-hypotension

7.37 ± 0.01

7.37 ± 0.01

7.31 ± 0.01αβ

7.33 ± 0.02

7.35 ± 0.01

 LPS-normotension

7.38 ± 0.01

7.35 ± 0.01

7.35 ± 0.01

7.35 ± 0.01

7.37 ± 0.01

pCO2 (mmHg)

 Saline control

47.2 ± 0.6

48.9 ± 1.3

49.7 ± 0.9

47.6 ± 1.0

48.9 ± 1.0

 LPS-hypotension

46.6 ± 1.5

47.2 ± 1.0

53.6 ± 1.7β

54.7 ± 1.8α

52.2 ± 1.0β

 LPS-normotension

47.0 ± 1.0

48.9 ± 1.7

46.9 + 2.3

48.9 ± 2.1

47.2 ± 1.3

pO2 (mmHg)

 Saline control

25.7 ± 1.2

27.1 ± 1.9

26.3 ± 1.9

24.9 ± 1.9

26.7 ± 1.9

 LPS-hypotension

25.7 ± 1.6

26.1 ± 1.6

24.2 ± 1.8

20.2 ± 1.2

21.7 ± 2.0

 LPS-normotension

25.4 ± 1.0

25.2 ± 1.3

25.4 ± 1.7

24.2 ± 1.9

22.5 ± 1.6

Lactate (mmol/L)

 Saline control

0.8 ± 0.1

0.7 ± 0.0

0.8 ± 0.0

0.8 ± 0.0

0.8 ± 0.0

 LPS-hypotension

0.9 ± 0.1

0.8 ± 0.1

1.5 ± 0.2αβ

2.9 ± 0.4αβ

1.7 ± 0.3

 LPS-normotension

0.6 ± 0.1

0.8 ± 0.1

0.9 ± 0.1

1.0 ± 0.2

1.0 ± 0.4

Glucose (mmol/L)

 Saline control

1.1 ± 0.1

1.2 ± 0.1

1.2 ± 0.1

1.2 ± 0.1

1.1 ± 0.1

 LPS-hypotension

1.0 ± 0.1

1.1 ± 0.1

1.1 ± 0.1

0.9 ± 0.0

1.0 ± 0.1

 LPS-normotension

0.9 ± 0.2

1.0 ± 0.1

1.0 ± 0.1

1.0 ± 0.1

0.9 ± 0.1

  1. Data are mean ± SEM. pCO2, partial pressure of carbon dioxide in arterial blood; pO2, partial pressure of oxygen in arterial blood. αLPS-hypotension vs. saline control, p < 0.05. βLPS-hypotension vs. LPS-normotension, p < 0.05.