Figure 2

Regional association plot for region around rs3184504.
Plots are produced in LocusZoom and show the most strongly associated SNP, rs3184504 (purple diamond). rs7137828, intron of ATXN2, is the SNP with the second lowest P value. The primary aim of this analysis is to compare association signals among SNPs in the region. Therefore, the data are derived from a meta-analysis of genotyped or high-quality imputed SNPs in the GWAS data sets and because imputation quality was more variable in iCOGS than in the GWAS data, the iCOGS samples are not included.