Figure 4 | Scientific Reports

Figure 4

From: Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1

Figure 4

Regional association plot for region around rs12970291.

Legend is as for Fig. 2, except as follows. The most strongly associated SNP from the full discovery meta-analysis (rs12970291, purple diamond) is not the most strongly associated in the GWAS data sets. The most strongly associated SNP, rs35185115, lies about 30kb downstream of TSHZ1, but this SNP imputed poorly in iCOGS and was therefore assessed in fewer samples in the discovery meta-analysis than rs12970291, which was directly genotyped in iCOGS.

Back to article page