Table 2 IC50 values for gefitinib as determined by MTT assay in our panel of EGFR-mutant cell lines.

From: BIM and mTOR expression levels predict outcome to erlotinib in EGFR-mutant non-small-cell lung cancer

Cells

Mutation

IC50* (μM)

H3255

L858R

0.003

PC-9

Del E746–A750

0.04

11–18

L858R

0.39

H1975

L858R, T790M

9.07

H1650

Del E746–A750

13.67

  1. *IC50: inhibition concentration of 50% cell viability.
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