Figure 2

PTZ elicits Long-term Potentiation.
(A) Schematic representation of hippocampal slice and the positioning of stimulating and recording electrodes. (B) PTZ treatment-dependent differential increase of field EPSP amplitude after theta burst-stimulation (black arrows) in Thra1+/+ and Thra1+/m hippocampus. Field EPSP amplitude in Thra1+/+ hippocampal area CA1 from animals treated with vehicle (black; n = 3) or PTZ (red; n = 3) (left panel). Field EPSP amplitude in Thra1+/m hippocampal area CA1 from animals treated with vehicle (black; n = 3) or PTZ (n = 3; red) (right panel).