Table 1 Three kinase fusion transcripts in endometrial cancer.

From: Novel kinase fusion transcripts found in endometrial cancer

Cell line

5′-Gene

3′-Gene

Locus 5′-Gene

Locus 3′-Gene

5′-Gene copy number*

3′-Gene copy number*

Discordant read (n)

Junction spanning read (n)

Frequency in clinical specimens

JHUEM3

CPQ

PRKDC

8q22.1

8q11.21

2

2

16

44

3/122 (2.5%)

HEC59

CAPZA2

MET

7q31.2

7q31.2

0

1

8

27

0/122 (0%)

AN3CA

VGLL4

PRKG1

3p25.3

10q21.1

−2

1

19

21

0/122 (0%)

  1. *Putative copy number was determined by GISTIC2 (−2 = homozygous deletion; −1 = hemizygous deletion; 1 = low level gain; 2 = high level amplification)
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