Figure 8 | Scientific Reports

Figure 8

From: Discovering new mTOR inhibitors for cancer treatment through virtual screening methods and in vitro assays

Figure 8

Effects of compound 17 on the mTORC1, mTORC2 and AKT activity in HeLa cells by Western blotting.

Inmunoblot analysis of phosphorylation blocking effects of 17 for p70SK6, 4E-BP1, Akt (S473) and Akt (T308) (Left). Quantitative measurement of the phosphorylation levels of these proteins (Right). β-actin was used as a loading control. *P <0.05 and ***P <0.001 versus control.

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