Table 3 Genotype and allele frequencies distribution of IL-10 and IL-18 polymorphism in Parkinson’s disease (PD) patients and health controls.
SNP | Genotype/allele | PD(n = 460) | HCs(n = 473) | p a | ORa (95%CIa) |
|---|---|---|---|---|---|
IL10 (−592 A/C) | C | 271(29.5%) | 305(32.2%) | 0.226 | 0.884(0.723–1.080) |
rs1800871 | T | 649(70.5%) | 641(67.8%) | ||
CC | 51(11.0%) | 47(9.9%) | 0.237 | 0.888(0.730–1.081) | |
CT | 169(36.7%) | 211(44.6%) | |||
TT | 240(52.3%) | 215(45.5%) | |||
IL10 (−819 T/C) | C | 273(28.4%) | 305(32.2%) | 0.295 | 0.899(0.736–1.097) |
rs1800872 | A | 647(71.6%) | 641(67.8%) | ||
CC | 53(11.5%) | 48(10.2%) | 0.309 | 0.903(0.745–1.098) | |
CA | 167(36.3%) | 209(44.2%) | |||
AA | 240(52.2%) | 216(45.6%) | |||
IL18 (−137 G/C) | C | 121(13.2%) | 113(12.0%) | 0.536 | 1.092(0.826–1.444) |
rs187238 | G | 799(86.8%) | 833(88.0%) | ||
CC | 10(2.2%) | 4(0.8%) | 0.535 | 1.093(0.826–1.446) | |
CG | 101(21.9%) | 105(22.2%) | |||
GG | 349(75.9%) | 364(77.0%) |
