Figure 5 | Scientific Reports

Figure 5

From: RETRACTED ARTICLE: TRIM25 blockade by RNA interference inhibited migration and invasion of gastric cancer cells through TGF-β signaling

Figure 5

Ectopic expression of TRIM25 reversed the effects of TGF-β inhibitor on the migration and invasion of MKN-28 cells.

(A) MKN-28 cells was transfected with control plasmid (NC) or expression plasmid encoding TRIM25. 48 h after transfection, expression of TRIM25 was analyzed by qRT-PCR and immunoblotting. (B,C) MKN-28 cells transfected with TRIM25 or NC and migration and invasion assay were performed in a transwell chamber containing either DMSO or 10 μM TGF-β inhibitor, SB431542 (Sigma). Scale bar: 100 μm.

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