Figure 1

Effects of vagus nerve stimulation on blood pressure.

(A) SBP increased significantly at week 12^th of HFD consumption. VNS significantly decreased SBP at week 16^th, week 20^th and week 24^th in obese-insulin resistance. (B) DBP increased significantly at week 20^th of HFD consumption. VNS significantly decreased DBP at week 16^th, week 20^th and week 24^th in obese-insulin resistance. (C) MAP increased significantly at week 20^th of HFD consumption. VNS significantly decreased MAP at week 16^th, week 20^th and week 24^th in obese-insulin resistance. Data were expressed as mean ± SEM. *p < 0.05 vs baseline, †p < 0.05 vs sham group, ‡p < 0.05 vs at 12 week after high-fat feeding of the same group, n = 8/group.