Figure 6

Effects of vagus nerve stimulation on cardiac mitochondrial function and morphology after 24 weeks of HFD consumption.
(A) VNS significantly reduced mitochondrial ROS production in obese-insulin resistance. (B) VNS significantly increased mitochondrial membrane potential change in obese-insulin resistance. (C) VNS significantly increased cardiac mitochondrial absorbance in obese-insulin resistance. (D) Representative images showing VNS dramatically prevented mitochondrial swelling. Data were expressed as mean ± SEM. *p < 0.05 vs. sham group, n = 8/group.