Table 1 Effects of vagus nerve stimulation on cardiac function after 24 weeks of HFD consumption.

From: Vagus Nerve Stimulation Improves Cardiac Function by Preventing Mitochondrial Dysfunction in Obese-Insulin Resistant Rats

Cardiac function

Sham

VNS

Heart rate (bpm)

302.1 ± 26.4

279.9 ± 10.1

ESP (mmHg)

133.2 ± 4.6

103.6 ± 11.3

EDP (mmHg)

24.3 ± 3.5

8.4 ± 1.9*

+dP/dt (mmHg/s)

11846.9 ± 2130.81

9026.6 ± 1205.4

−dP/dt (mmHg/s)

−12129.3 ± 2638.9

−29903.1 ± 5629.3*

SV (μl)

486.1 ± 18

619.8 ± 15*

SW (mmHg.μl)

57626.2 ± 1462.4

53635.9 ± 2847.9

  1. Data were expressed as mean ± SEM. *p < 0.05 vs. sham group, n = 8/group.
  2. ESP, end-systolic pressure; EDP, end-diastolic pressure; +dP/dt, maximal slope of the systolic pressure increment; −dP/dt, maximal slope of the diastolic pressure decrement; SV, stroke volume and SW, stroke work.
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