Table 1 Overall statistics of the subtractive proteome approach for drug target identification of the wBm.
Unique Pathway Proteins (UPP) Analysis | Proteins In Numbers | Common Pathway Protein (CPP) Analysis | Proteins In Numbers |
|---|---|---|---|
Unique pathway proteins (UPP) | 50 | Common pathway proteins (CPP) | 460 |
Excluded repeated proteins from CPP | 01 | Excluded repeated proteins from CPP | 49 |
| Â | Â | Excluded common proteins between CPP and UPP | 14 |
| Â | Â | Total proteins | 397 |
Homologous to human | 13 | Homologous to human | 298 |
Non-homologous to human | 37 | Non-homologous to human | 119 |
Non-Homologous To Human Proteins From UPP And CPP | |||
 Total Non-homologous protein sequences |  | 156 | |
 Essential proteins (Homologous to DEG) |  | 115 | |
 Protein sequence less than 100 amino acid |  | 10 [115−10 = 105] | |
Subcellular localization [Gneg-mPLoc] | |||
 Drug targets [Cytoplasm, Inner membrane, Periplasm] |  | 101 [75 + 22 + 4 = 101 ] | |
 Vaccine targets [Extracellular] |  | 4 | |
Druggability | |||
 DrugBank |  | 56 | |
 TTD |  | 25 | |
 Common between DrugBank and TTD |  | 20 | |
 Total druggable targets |  | 61 | |
 Total potential druggable drug targets of wBm |  | 61 | |
