Figure 5

The effect of microinjection of antalarmin, antisauvagine-30 and astressin into the PH on the increased HR response by microinjection of CRF into the PH.
(A) Changes in HR, evoked by microinjection of CRF into the PH and the CRF-induced changes after microinjection of antalarmin, antisauvagine-30 and astressin. (B) Group data showing the CRF-induced changes in average peak HR in rats before and after microinjection of CRF receptor antagonists. Statistical significance was determined using Student’s t test. *P < 0.05, **P < 0.01.