Figure 8 | Scientific Reports

Figure 8

From: The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release

Figure 8

Effect of treatment on in vivo susceptibility of S. aureus.

(a) Log CFU/nematode (average ± s.d.) in C. elegans nematodes infected with S. aureus Mu50 or Newbould 305, receiving no treatment or a treatment with HAM, VAN or a combination of VAN and HAM (COMB). (b) Log CFU/g mammary gland (average ± s.d.) of mice infected with S. aureus Newbould305 receiving no treatment or a treatment with HAM, CFL or a combination of CFL and HAM (COMB). (c) Histological evaluation of mammary glands of mice infected with S. aureus Newbould305 receiving no treatment or a treatment with HAM, CFL or a combination of CFL and HAM (COMB). Arrows indicate influx of neutrophils. *significant differences in log CFU/nematode (a) or log CFU/g mammary gland (b) between the indicated samples (p < 0.01).

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