Figure 5
From: CRISPR/Cas9-mediated gene knockout in the mouse brain using in utero electroporation
CRISPR/Cas9-mediated mutations in the Satb2 locus.
(a) Representative mutations found in the Satb2 locus. The wild-type sequence of the Satb2 gene and five representative mutations are shown. The PAM sequence is marked in red. Green dashes and blue bases indicate deletions and insertions, respectively. The numbers in parentheses indicate the number of bases that had been changed. (b) A pie chart showing frequencies of out-of-frame and of in-frame mutations found in the Satb2 gene.
