Figure 6
From: Redifferentiation of expanded human islet β cells by inhibition of ARX
Effect of ARX inhibition in sorted expanded ACD cells.
(a) Immunofluorescence analyses of islet endocrine cell types before and after sorting of α cells. Values are mean ± SE (n = 3 donors), based on counting >1000 cells per donor. (b) Immunofluorescence analyses of C-peptide in sorted α cells infected at passages 3–5 with ARX or control shRNA viruses and treated with RC for 4 days. Values are mean ± SE (n = 3 donors), based on counting >1000 cells per donor.
