Figure 1
From: Pax6 in Collembola: Adaptive Evolution of Eye Regression
Collembolan Pax6 is more similar to insect Ey than to insect Toy.
(A–B’) Pictures of studied collembolans (with permission granted by the photographer, Dr. Feng Zhang). (A) The eyeless F. candida. (A’) The head of F.candida, dorsal view. (B) The eyed C. denticulata with the eye fields indicated by the blue arrows. (B’) Eight ocelli on the left side of the head of C. denticulata. (C) The heatmap shows percent identity over the Fc-Pax6 and Cd-Pax6 amino acid sequence compared with Ey and Toy from the T. castaneum. The red rod and the blue rod demonstrate amino acid sequences of Fc-Pax6 and Cd-Pax6, respectively. The line in green shows comparisons using T. castaneum Ey as a query sequence and the line in brown shows comparisons using T. castaneum Toy as the query. The N-terminus (NT), Paired domain (PD), Linker region B, Homeodomain (HD) and C-terminus (CT) of Fc-Pax6 and Cd-Pax6 are labeled on the rods, with alignment sites of amino acid sequences. (D) The phylogenetic tree using neighbor-joining method for hexapod Pax6 homologs, based on first and second codon positions of PD and HD. Bootstrap values are indicated at the nodes. Clade-specific significant amino acids of PD (positions 12, 14, 64 and 85) are marked on the corresponding branches.
