Figure 2: Ventana in situ hybridization in benign cervical samples.

(a) A representative example of Ventana ISH showing the presence of HPV in the transformation zone (BC 54); (EC - endocervical gland). The left panel shows the results from Ventana ISH staining x 10 magnification and the right panel shows a higher magnification (60X) of the region indicated by a box. (b) Representative examples of a HPV positive (BC 28) and a HPV negative (BC 105) benign cervix sample. The left panel shows the results from Ventana ISH staining x 20 magnification and the right panel shows a higher magnification (60X) of the region indicated by a box. In sample BC 28, blue punctate staining is observed in the nuclei of basal and suprabasal cells.