Figure 4: Result of the meta-regression analysis demonstrating that the symptom severity (HAMD scores) of MDD patients is negatively correlated with FA in the genu of the CC. | Scientific Reports

Figure 4: Result of the meta-regression analysis demonstrating that the symptom severity (HAMD scores) of MDD patients is negatively correlated with FA in the genu of the CC.

From: Disorganization of white matter architecture in major depressive disorder: a meta-analysis of diffusion tensor imaging with tract-based spatial statistics

Figure 4

In the graphs, AES-SDM values needed to create this plot were extracted from the peak of maximum slope significance, and each study is represented as a dot; the dot size reflects the sample size. The regression line (meta-regression signed differential mapping slope) is presented as a straight line. Abbreviations: FA, fractional anisotropy; CC, corpus callosum; MDD, major depressive disorder; HAMD, Hamilton Depression Rating Scale; AES-SDM, anisotropic effect size-signed differential mapping.

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