Table 1 Mutant clone ratios detected by ddPCR.
Mut clone ratios | Mut copy number * | Mut drop number | Wt drop number | ACD | FA (%) | FA range (%) |
|---|---|---|---|---|---|---|
10% | 144 | 101 | 707 | 16444 | 12.3 | 14.5–10.0 |
10% | 166 | 114 | 754 | 16252 | 12.9 | 15.1–10.7 |
10% | 150 | 103 | 1046 | 16196 | 8.7 | 10.3–7.1 |
5% | 74 | 50 | 771 | 15951 | 6 | 7.6–4.3 |
5% | 74 | 49 | 714 | 15547 | 6.3 | 8.0–4.6 |
5% | 66 | 48 | 1050 | 16941 | 4.2 | 5.4–3.1 |
1% | 14.4 | 9 | 681 | 14684 | 1.3 | 2.1–0.4 |
1% | 10.2 | 7 | 729 | 16037 | 0.9 | 1.6–0.2 |
1% | 16 | 11 | 1182 | 16282 | 0.9 | 1.4–0.4 |
0.50% | 8.6 | 5 | 576 | 13723 | 0.8 | 1.6–0.1 |
0.50% | 4.6 | 3 | 552 | 15250 | 0.5 | 1.2–0 |
0.50% | 8.8 | 6 | 1031 | 16030 | 0.56 | 1.02–0.1 |
0.25% | 5 | 3 | 679 | 14038 | 0.43 | 0.95–0 |
0.25% | 3.6 | 2 | 631 | 12837 | 0.31 | 0.78–0 |
0.25% | 4.2 | 3 | 1104 | 16872 | 0.26 | 0.58–0 |
0.10% | 0 | 0 | 772 | 16230 | 0 | 0–0 |
0.10% | 1.4 | 1 | 788 | 16400 | 0.12 | 0.42–0 |
0.10% | 3.4 | 2 | 975 | 13931 | 0.2 | 0.50–0 |