Figure 3

Kaplan-Meier curve analysis according to pre- and post-treatment variation of LDH serum levels (decreased, 35 pts— vs. increased, 79 pts -------): (a) mPFS: 6.2 vs. 3.0 months (p = 0.0009; HR = 0.49; 95% IC: 0.33–0.74); (b) mOS: 12.1 vs. 5.1 months (p < 0.0001; HR = 0.42; 95% IC: 0.27–0.63).