Figure 6 | Scientific Reports

Figure 6

From: Encapsulation of zinc-rifampicin complex into transferrin-conjugated silver quantum-dots improves its antimycobacterial activity and stability and facilitates drug delivery into macrophages

Figure 6

Antibacterial and cytotoxic activity of Zn-Rif-Tf-QDs.

Dose dependent killing of M. bovis-BCG by Zn-RIF, Tf-QDs, RIF and Zn-RIF-Tf-QD after (A) 6 h and (B) 24 h. Bacteria were incubated with different concentrations of Zn-RIF, Tf-QDs, RIF and Zn-RIF-Tf-QD and their survival was determined at the indicated time points by CFU assay. Media containing bacteria alone was used as control and the corresponding concentrations of RIF and Zn(NO3) present in respective doses of Zn-RIF complex were used as rifampicin and Zn(NO3) controls, respectively. Experiments were performed in triplicates, results are shown mean ± SD; ***P ≤ 0.001.

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