Figure 1 | Scientific Reports

Figure 1

From: An Allosteric Cross-Talk Between the Activation Loop and the ATP Binding Site Regulates the Activation of Src Kinase

Figure 1The alternative text for this image may have been generated using AI.

Comparison of inactive (Left, PDB id: 2SRC) and phosphorylated, active (Right, PDB id: 1YI6) crystal structures of the Src catalytic domain.

Key structural elements are colored in red (αC helix), blue (P-loop), yellow (A-loop) and green (αF helix). The (P)-Tyr416 and ATP are shown as sticks. The C- and R-spines are shown as surfaces (with inner residues as sticks) in cyan and pink, respectively.

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