Figure 9

TEM for cellular investigation.
(a) Cells in a tumor that was not treated. (b) Magnified image of the area indicated by the rectangle in (a). (c–e) AuNDs located in tumors treated with PPTT for only 30 seconds. Black arrows in (c): disrupted sites of cellular membrane. White stars in (c): intact AuNDs. (f) After AuNDs-assisted PPTT is performed for 5 minutes, no droplets or bubbles were found and the cellular structures no longer appeared integrated. (g) Magnified image of the area indicated by the rectangle in (f). Many free AuNRs are evident throughout the fractured cells.