Figure 3: Mechanical behaviors of mutated and segmented α-catenin.
From: Mechano-adaptive sensory mechanism of α-catenin under tension
(A) Contour map for MT MI-MIII fragment based on 576 force curves. (B) Comparison of the number density nd in contour maps from a side view in WT and MT MI-MIII fragments. (C) Contour maps for MI and MII–MIII fragments based on 181 and 785 force curves, respectively. The contour map for MII–MIII fragment is shifted to the right by 46.8 nm, which corresponds to the fully-extended length of MI domain. (D) The average number of force peaks N per curve. The stacked bar graphs display N values, with color intensity illustrating the range of transition force ΔFT. The substructure stability increases with the increasing ΔFT values.
