Figure 1 | Scientific Reports

Figure 1

From: Slug-upregulated miR-221 promotes breast cancer progression through suppressing E-cadherin expression

Figure 1

Restore E-cadherin expression in tumor cells using wild type (WT) E-cadherin-expressing vector and compared the levels of E-cadherin protein and mRNA transcript at various time points.

(a,b) E-cadherin protein levels (a) and mRNA levels (b) in MCF-7 and MDA-MB-231 cells. (c) Confocal immunofluorescent images of E-cadherin levels in MCF-7 cells and MDA-MB-231 cells. (d,e) E-cadherin mRNA levels (d) and protein levels (e) in MCF-7 and MDA-MB-231 cells transfected with WT E-cadherin-expressing vector (E-cad) for 0, 24, 48 or 72 h. Results are presented as the mean ± SEM (n = 3). *P < 0.05. **P < 0.01.

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