Table 1 S. japonicum EV proteins are homologous to exosomal proteins in other species.
Description of the identified proteins in S. japonicum EVs | Homologs of exosomal proteins in other species | E value $ | Identities (%) | ||
|---|---|---|---|---|---|
Plasma | Cells | Parasites | |||
Actin | √50 | √51 | √27 | 0 | 91 |
26 S proteasome regulatory subunit T3 | √52 | 0 | 89 | ||
Proteasome (Prosome, macropain) 26 S subunit, ATPase 2 | √27 | 0 | 88 | ||
Proteasome (Prosome, macropain) 26 S subunit, ATPase 3 | √52 | 0 | 83 | ||
Eukaryotic translation elongation factor 1 alpha 2 | √51 | √27 | 0 | 81 | |
CDC42 protein | 2.00E-109 | 78 | |||
26 S proteasome regulatory subunit N11 | √54 | 3.00E-179 | 78 | ||
Glyceraldehyde 3-phosphate dehydrogenase | √50 | √51 | √19 | 0 | 75 |
Heat shock protein 70 | √53 | √51 | 0 | 72 | |
Glucose-6-phosphate isomerase | √53 | 0 | 70 | ||
Proteasome subunit beta type 5 | √52 | √26 | 7.00E-102 | 70 | |
Heat shock protein 90 | √53 | √52 | √14 | 0 | 68 |
Phosphoglycerate kinase | √54 | 0 | 68 | ||
Rab-protein 11 | √54 | 2.00E-89 | 68 | ||
Proteasome (Prosome, macropain) subunit alpha type 4 | √51 | √27 | E-118 | 67 | |
Glutamine synthetase | √53 | 0 | 66 | ||
26 S proteasome non-ATPase regulatory subunit 7 | 6.00E-126 | 66 | |||
Rab-protein 10 | √53 | √54 | √19 | E-89 | 65 |
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 6.00E-112 | 64 | |||
Lactate dehydrogenase | √54 | 2.00E-144 | 61 | ||
Proteasome subunit beta type 6 | √26 | 2.00E-87 | 61 | ||
20 S proteasome subunit alpha 7 | √52 | √27 | 3.00E-105 | 60 | |
Proteasome subunit beta type 7 | √54 | √26 | 9.00E-117 | 60 | |
