Figure 2: Development of a rat diabetes model.
From: VEGF-B inhibits hyperglycemia- and Macugen-induced retinal apoptosis
(A) A streptozotocin (STZ)-induced diabetes rat model was established by a single intraperitoneal injection of streptozotocin. Blood glucose levels of the rats were carefully monitored at different time points. (B) After STZ injection, blood glucose levels of the rats measured at different time points were significantly higher than those of the control group. (C) STZ treatment led to progressive loss of body weight in the streptozotocin-treated rats. Two-tailed Student’s t-tests were performed using independent samples. **P < 0.01.
