Table 2 Micronucleus tests with SET-M33L peptide in human lymphocytes.
Compound/concentration (μg/ml) | Mean of binucleate cells containing micronuclei per 1000 cells | ||
|---|---|---|---|
3h − S9 | 3h + S9 | 20h − S9 | |
vehicle (control) | 6.3 | 6.3 | 9.5 |
SET-M33L/7.5 | 6.0 | 4.0 | 8.5 |
SET-M33L/150 | 6.0 | NA | NA |
SET-M33L/300 | NA | 5.5 | 8.5 |
SET-M33L/350 | 7.0 | NA | NA |
SET-M33L/400 | NA | 6.0 | 9.5 |
MMC/0.2 | 28.0 | NA | NA |
MMC/0.05 | NA | NA | 22.5 |
COL/0.06 | 20.5 | NA | NA |
COL/0.01 | NA | NA | 19.0 |
CPA/10 | NA | 17.0 | NA |
