Figure 1: pH1N1 Ab maturation occurs within 7 days after TIV. | Scientific Reports

Figure 1: pH1N1 Ab maturation occurs within 7 days after TIV.

From: ICOS+PD-1+CXCR3+ T follicular helper cells contribute to the generation of high-avidity antibodies following influenza vaccination

Figure 1

(a) The amount (Max RU) and the avidity (Kd) of serum polyclonal Abs specific for pH1N1 HA1 at day 0, 7, and 28 post-TIV were determined by surface plasmon resonance. Paired t-test. ***p-value < 0.001, n = 26. (b) The correlation between Max RU and Kd of serum polyclonal Abs against pH1N1 HA1, and HI and VN titers. Results of day 0 and day 28 post-TIV. Spearman R and p-value are indicated. n = 52. (c) The correlation between the fold increase of Max RU/the fold decrease of Kd at day 28 and the increase of HI and VN titers at day 28. Spearman R and p-value are indicated. n = 26.

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