Table 2 The metabolic parameters after 12-week of VNS treatment in comparison with the sham group.

From: Vagus Nerve Stimulation Exerts the Neuroprotective Effects in Obese-Insulin Resistant Rats, Leading to the Improvement of Cognitive Function

Metabolic parameters

12 weeks post-treatment

Sham

VNS

Body weight (g)

613.34 ± 8.97

594.17 ± 10.83

Food intake (g/day)

19.28 ± 1.61

19.46 ± 1.22

Visceral fat (g)

61.01 ± 2.61

51.92 ± 3.53*

Plasma glucose (mg/dl)

131.47 ± 9.60

134.46 ± 3.98

Plasma insulin (ng/ml)

4.85 ± 1.36

3.04 ± 0.42*

HOMA index

30.93 ± 10.85

18.12 ± 2.37*

Plasma glucose AUC (AUCg) (mg/dl × min × 104)

5.58 ± 0.27

4.70 ± 0.23*

Plasma total cholesterol (mg/dl)

105.93 ± 6.34

81.42 ± 2.66*

Plasma total triglyceride (mg/dl)

28.73 ± 3.05

19.64 ± 1.60*

HDL cholesterol (mg/dl)

27.94 ± 1.67

27.39 ± 0.95

LDL/VLDL cholesterol (mg/dl)

70.17 ± 5.79

48.62 ± 1.63*

  1. *p < 0.05 in comparison with the sham group.