Figure 4: Tree of 238 residues with contribution to at least one studied sNRI in binding hNET by hierarchically clustering their energies. | Scientific Reports

Figure 4: Tree of 238 residues with contribution to at least one studied sNRI in binding hNET by hierarchically clustering their energies.

From: Exploring the Inhibitory Mechanism of Approved Selective Norepinephrine Reuptake Inhibitors and Reboxetine Enantiomers by Molecular Dynamics Study

Figure 4

The residues favoring sNRI’s binding are colored in red (the one with the highest contribution was colored as standard red and the lower contribution one was set to fade gradually to white). In the meantime, the residues hampering sNRI’s binding are displayed in blue (the highest one was colored as standard blue and the lower one was set to fade gradually to white). The white color here denotes residue with no contribution to sNRIs’ binding.

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