Figure 8: Superimposition of and conformation variation between (R, R)-reboxetine (in cyan) and (S, S)-reboxetine (in light pink) together with their interacting residues (in corresponding color). | Scientific Reports

Figure 8: Superimposition of and conformation variation between (R, R)-reboxetine (in cyan) and (S, S)-reboxetine (in light pink) together with their interacting residues (in corresponding color).

From: Exploring the Inhibitory Mechanism of Approved Selective Norepinephrine Reuptake Inhibitors and Reboxetine Enantiomers by Molecular Dynamics Study

Figure 8

(A) Conformational changes of ligands and residue Asp75 were displayed; (B) conformational changes of ligands and residues Val148, Tyr152, Ser420, Gly423 and Met424 were illustrated. The salt bridge interaction was displayed in red dashed line and the hydrogen bond interaction was in green.

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