Table 2 Univariate association of main clinico-biological characteristics and tissular microRNA with renal failure-free survival.

From: miR-21-5p renal expression is associated with fibrosis and renal survival in patients with IgA nephropathy

 

Hazard Ratio

95% confidence interval

p-Value

Clinico-biological data

 Systolic blood pressure*

1.59

1.29–1.97

<0.0001

 Proteinuria†

1.57

1.30–1.89

<0.0001

 eGFR‡

0.32

0.18–0.55

<0.0001

microRNA

 miR-21-5p ≥2.06

4.08

1.32–12.55

0.014

 miR-214-3p ≥1.60

3.81

1.06–13.74

0.041

 miR-199a-5p

NA

  
  1. eGFR: estimated Glomerular Filtration Rate, NA: Non Applicable. hazard ratio expressed per *10 mmHg increase of systolic blood pressure, †1 g/day increase of proteinuria and ‡10 mL/min/1.73 m2 increase of eGFR.
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