Table 1 Amino acid sequences, formula, molecular weights, charge, and hydrophobicity values of the peptides used in this study.

From: Antimicrobial activity, improved cell selectivity and mode of action of short PMAP-36-derived peptides against bacteria and Candida

Peptides

Sequence

Formula

Theoretical MW

Measured MW a

Net Charge

H b

PMAP-36 c

GRFRRLRKKTRKRLKKIGKVLKWIPPIVGSIPLGCG-NH2

C191H337N63O38S1

4156.20

4156.27

+14

−1.41

RI21

RRLRKKTRKRLKKIGKVLKWI-NH2

C124H231N45O22

2704.40

2704.51

+13

−3.10

RI18

RKKTRKRLKKIGKVLKWI-NH2

C106H196N36O19

2278.90

2278.97

+11

−3.05

TI15

TRKRLKKIGKVLKWI-NH2

C88H160N28O16

1866.40

1866.43

+8

−1.67

RI12c

RLKKIGKVLKWI-NH2

C72H129N21O12

1480.90

1480.94

+6

−0.11

  1. aMolecular weight (MW) was measured by MALDI-TOF mass spectroscopy.
  2. bThe mean hydrophobicity (H) was the total hydrophobicity of per residue of peptides calculated using CCS scale.
  3. cPMAP-36 and RI12 physicochemical parameters were determined as previously described15.
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