Table 2 GO functional enrichment analysis of DEGs between NFs and INFs.

From: Stromal fibroblasts derived from mammary gland of bovine with mastitis display inflammation-specific changes

Gene ontology term

Cluster frequency*

Genome frequency of use

Corrected P-value

Terms from the Component Ontology

 extracellular matrix

22/422

163/10103

0.00013

 kinetochore

11/422

47/10103

0.00033

 extracellular region

43/422

492/10103

0.00038

 chromosome

30/422

323/10103

0.00413

Terms from the Function Ontology

 oxidoreductase activity

4/422

6/9897

0.00945

Terms from the Process Ontology

 cholesterol metabolic process

11/429

33/9543

0.00012

 regulation of developmental process

38/429

381/9543

0.00339

 negative regulation of developmental process

17/429

109/9543

0.00756

 tissue development

39/429

413/9543

0.00937

 negative regulation of cellular process

56/429

688/9543

0.00985

  1. *Cluster frequency: the denominator represents the total number of genes with GO annotation and the numerator represents the number of each GO term genes. Genome frequency of use: the denominator represents the number of reference genes with GO annotation and the numerator represents the number of reference genes annotated in the listed GO term. Corrected P-value: P-value in hypergeometric test after correction.
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