Table 4 Association between the MTRR 66A > G dominant model and survival of gastric cancer patients among various chemotherapy regimen subgroups.
MTRR66A > G | |||||
|---|---|---|---|---|---|
Chemotherapy Based on DDP and 5-FU | |||||
Genotype | Patients, n = 140 | Deaths, n = 69 | MST (months) | log-rank p | HR (95% CI) a |
AA | 90 | 47 | 50 | 0.494 | 1 |
GA/GG | 50 | 22 | 60 b | 0.839 (0.506–1.393) | |
Chemotherapy Based on L-OHP and 5-FU | |||||
Genotype | patients, n = 140 | Deaths, n = 46 | MST (months) | log-rank p | HR (95% CI) a |
AA | 65 | 27 | 62 | 0.035 | 1 |
GA/GG | 75 | 19 | 92 b | 0.538 (0.299–0.970) | |